Selphyl PRFM

Sabeen Munib, MD

Selphyl PRFM Hair Restoration in Irvine, CA

Selphyl PRFM (Platelet-Rich Fibrin Matrix) is an advanced, natural hair restoration treatment that enhances your body’s healing ability to stimulate hair regrowth. Unlike traditional PRP (Platelet-Rich Plasma), PRFM includes a fibrin matrix that releases growth factors gradually, extending their regenerative effects. At Spectrum Skin Clinic, we use Selphyl PRFM to help restore thicker, stronger, and healthier hair in both men and women experiencing early to moderate hair thinning.

What is PRFM and how does it work for hair loss?

PRFM is a next-generation form of PRP (Platelet-Rich Plasma). It is processed using the Selphyl system, which creates a fibrin matrix that holds and slowly releases growth factors over time. When injected into areas of thinning hair, these growth factors:

• Stimulate stem cells around hair follicles

• Prolong the growth (anagen) phase of hair

• Improve scalp circulation and follicle health

• Increase hair shaft thickness and density


Because PRFM is autologous (from your own body), it’s biocompatible and very well-tolerated.

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What concerns can PRFM treat?

• Early-stage male or female pattern hair loss (androgenic alopecia)

• Postpartum shedding or stress-related hair loss

• Thinning in the crown, temples, or hairline

• Preventative care for patients with a family history of hair loss

• Patients not candidates for oral medications or hair transplants

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What can I expect during the procedure?

The procedure begins with a simple blood draw. Your blood is processed using the Selphyl system to isolate the PRFM, which is then injected into targeted areas of the scalp. The treatment takes about 45–60 minutes and is performed in-office. Most patients describe the sensation as mild to moderate pressure with brief discomfort.

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What is the downtime and recovery?

There is no true downtime. You may experience mild swelling or sensitivity at the injection sites for 24–48 hours. We advise avoiding hair washing, exercise, or scalp manipulation for the rest of the day. You can return to normal activity immediately after.

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When will I see results, and how long do they last?

You may notice reduced shedding within a few weeks, with visible thickening and regrowth in 2–3 months. Full results appear over 3–6 months as hair cycles improve. Most patients require a series of 3 sessions spaced 4–6 weeks apart, followed by maintenance every 6–12 months.

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Who performs the procedure?

Selphyl PRFM treatments at Spectrum Skin Clinic are performed by trained medical professionals under the supervision of Dr. Sabeen Munib. Each treatment plan is tailored based on the degree of hair loss, underlying causes, and patient preferences.

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Frequently Asked Questions

Got questions? We’re here to help! Find out what we offer, how to book an appointment, where we’re located, and more. We treat all age groups and offer skincare products too.

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